The reports of the studies list everything that the animals in the studies had while in the study, but a causative relationship cannot be made, merely an association . He keep vomiting and now cant Key Points on Apoquel Unlike steroids, Apoquel side effects are minimal: no excessive thirst or hunger, no exces-sive urination, and no long-term negative effects on the liver Apoquel can cause rare intermittent GI symptoms For a 45-lb. Heres a handy chart to help you figure out the right dosage for your pup: Mutasim is an author and software engineer from the United States, I and a group of experts made this blog with the aim of answering all the unanswered questions to help as many people as possible. Dogs have 10 times more mast cells on their skin than people do. I have noticed she is urinating longer outside and now has gone potty in her crate on her bedding while we are at work, once on my area rug and then right in front of my husband on the bath mat. He has now lost hair all over his body. I have a 90 pound mixed male Shar pei who has been on Apoquel 3 years now. Its like there is flem in is throat and he cant catch his breath. Dogs are able to take hydroxyzine. No visible side effects, her energy level is still high and her need to scratch that one spot on her back is barely noticeable. I have a St. Bernard Therapy Dog who had allergies, itching ears and feet. This year her suffering became unbearable. I have her now on a strict diet with premium dog food from Four Friends and Ropodog and the situation has much improved. Hydroxyzine (brand names: Atarax, Vistaril, Masmoran, Multipax) is an antihistamine used to treat allergic and itchy conditions or as a sedative/tranquilizer. Common names: chlorpheniramine, chlorpheniramine maleate. Apoquel also isn't recommended for dogs who have serious infections or for dogs who weigh less than 6.6 pounds. And dont forget if youre at all concerned about your pets medication, then give your veterinarian a quick ring. This drug works He has been on Prednisone since he was 10. I have had her since she was 6 mths old and she is now an old lady at 13. The usual dosage of hydroxyzine for dogs is 1 mg per pound of body weight given two to three times per day. I am going to let my Vet know. My 12 year old German Shepard mix was prescribed Apoquel for seasonal allergies after Zyrtec wasnt effective. No more apoquel. Last week we had to say goodbye. The internist believes that continuing the Apoquel any further (would) wreak havoc in his immune system, that we can only expect more papilloma lesions, further inflammation of his lymph nodes, lower platelet cell cell count and so on.". 5 days later & I still have a very very different dog He went from an extremely confident, friendly & vocal dog who was running round & playing all the time with my other dog into & nervous wreck & he also seems to still have discomfort in his bad leg. Apoquel cannot be used for dogs under one year or breeding, pregnant, or lactating . Her liver enzymes, glucose reading were off the charts. I called the vet but they said she must have eaten something to cause it. He has also been drinking excessively since we started him on the drug and peeing in the house as well. Feel free to share any questions and experiences in the comments section below. I started her on 1/2 tab once a day every day for the last month and 1/2. So, it is important that you only give this medication to your dog under your vets supervision. Vet Dermatol 2013;24:587-597.). I never, ever, leave my dogs side when they are a procedure until they are out, but this one was brutal. Drugs that suppress the immune system 5 days on Apoquel and she went to the kennel. She began taking it in Nov. Of 2019. So I would take care to note if you see her drinking more than usual. management. I was at my wits end after failing to relieve his itch, but I refuse to subject my love to seizures and liver damage. Im convinced its from this med!!! I know my Dog, . 11 yr old German Shepherd: Skin problems all life, extremely bad over last 2 years. He refused to eat or drink water for hours. Go ahead with apoquel. It started as seasonal allergies but he ended up itching all year round. After 3 pills he started having seizures. Antihistamines can also be used to treat anxiety, and to calm patients before general anesthesia and surgery. He was a totally healthy dog before Apoquel! It makes me sick to my stomach to see so many vets pushing and advertising this. We will continue with weekly medicated baths and if necessary will increase frequency of these. THIS STUFF OUT LIKE CANDY This is a 10 year old dog we never had problems leaving while we were at work and we spent the months of November, December 2016 trying to take turns going to work, (fortunately we had the flexibility). Along with this, came the increased urination. It could be fleas or mites, a food allergy, a secondary infection (such as yeast or bacteria). The bonding after reviving her is incredibly tight. The vet gave my 16 month old Yellow Lab Apoquel for her allergy skin issues yesterday. I will need to confine her if she continues to pee everywhere. Gabapentin should start to take effect fairly quickly, and relief should be noticed within one or two hours of administration. We finally got to take his cone off and start to enjoy walks again fully and his paws turned back to their original colorwhite! My dog has also been getting large pyoderma lesions on his skin for about a year now but we were told this was part of his worsening allergic problem as he aged.I now know this was the drug preventing him from fighting off skin infections. I am very upset after reading about this that our vet never advised to watch for side effects. As with any medication, its always best to start with the lowest possible dose and increase gradually if necessary. I stopped the pills immediately. And I know she picked the profession she did because of a passion for animals. of the development of severe pyoderma (after day 19) and one dog withdrew because of the I can not believe this is on the market with how many dogs have had issues from it. It took about 3 months for her red blood cells to start reproducing and return to normal. But, I did notice your office carried CET chews, Metacam, and Baytril. I believe it is the medication that has caused them. Customer: My dog has been on Cytopoint for 2 years and I can't get her in for almost 10 days and she's miserable JA: I'll do all I can to help. Apoquel is an anti-inflammatory medication used to treat allergic dermatitis, while Zyrtec is an antihistamine used to treat allergies. A dog who never once peed in the house, started having accidentswhen she was on a morning, noon, evening and bedtime schedule. I will never place another animal on a medication like this again. He has symptoms of Cushings from longterm use of the Pred and he has a heart murmur. After this, your vet will assess the situation and decide whether to prescribe antihistamines that are to be taken on a more regular basis. start with the lowest possible dose and increase gradually if needed. Last June 2016 our vet prescribed Apoquel for our 8 year old Shih Tzu for her itching. I hate that we now must take him off the medicine because he has been able to live a more comfortable life, but I cant ignore the side effects and how its affecting him. Because most of the placebo dogs dropped out, they really couldnt compare the groups. What Does Altered Dog Mean? He has always had allergies, some seasons are worse than others. After several visits to the veterinary center and medications including certrizine, hydroxyzine, loratadine, prednisone the veterinarian suggested trying Apoquel in December 2016. After the allergy tests I gave him Natural Balance Sweet Potato and Fish, which he doesnt eat much so I add other things to it. to determine what has happened. Here is my dilemma. He seemed afraid to move, as if it caused him pain. I knew all the side effects and finally was relieved to try the apoquel against my better judgement. The potential for serious side effects is substantial, and that 1/3 of dogs did not respond in the study. No they are not some very serious side effects have not been listed. Died in hospital where we had to carry her. We give her oatmeal baths and it dont help. was up all night with the poor little guy, he was panicking badly, jumping into my lap, whimpering, panting,he was doing a weird head stretch thing ,could not settle, drinking loads stopped the apoquel,took him to emergency vet, had bloods etc checked & they said he was fine. dog? Initially, his itching nearly subsided after staring Apoquel however, not for long. Not taking any chances! 1 [deleted] 8 yr. ago A typical dose is 1 mg per pound in dogs every 6-8 hours. esophagus to close keeping it enlarged (side effect). if taken off at all for one day she would lose all her hair in clumps and have sores all over where she licked or bit or scratched. They were both prescribed Apoquell July 2016 over the next few months one dog developed two small growths on his feet that were removed and one found to be malignant the other benign. 2 days ago, on daily dosing st this point, he had another. He seemed to be cured. I should have ask questions I usually do. Im starting to think all these different vaccines may not be such a good idea. She has had none of the issues above. Two days later he was at deaths door. Im anxious to see what happens. He is about 3 yrs old. Being very worried, I began doing research on the Apoquel the vet had given her and was shocked to find out its an immunosuppressant with some ugly side effects. Something has to be done. I talked with a Homeopathic vet about my dog and this med and she said that she is seeing at least 4 dogs a week that are coming to her because of reactions to APOQUEL. We gave her omega fatty acids, removed the grass out of our yard and eliminated environmental threats the best we could. I am having the same issue as Kelly noted above. Anything that prevents the immune system from functioning properly is dangerous. Metronidazole (also known by the brand names Flagyl, Metizol, Protostat, Metrogel) is a strong antibiotic primarily used as an antidiarrheal to treat inflammation of the large intestine. I AM STOPPING THIS MED TODAY! Feed your dog a simple food that he is less likely to react to. The most horrible thing I was witness to.His right eye sunk in to his skull. I noticed that he seemed a little lethargic after the first pill, but didnt feel alarmed since its supposed to do that. People need to look at tbeir vetwhat has been tried first. among the oclacitinib group compared with placebo (2.6% vs. 0%, respectively). An OTC alternative might be Benadryl for your dog. Apoquell is not the wonder drug they promise, for us it was a curse. Ive never had major issues with veterinarian medicines for my pets. My 11 Yorkie mix has had allergiesitchy feet mostly but all over at times, that we have tolerated as holisticly as possible his whole lifewith the occasional Benadryl. The one that was having panic attacks, lost weight, had quickly growing malignant growths and bizarre behavior has returned to normal other then weight, even though his appetite is back. Within a day he began acting different lethargic and mildly aggressive but he never stopped itching. Im praying Im not too late. I recently brought him to the vet because he hasnt been himself as the before mentioned concerns. and chemistry). Cons: Im not continuing the apoquel! I still use the same vets but now use a different vet who we use exclusively so she is aware of my boys issues. My puppy is exhibiting the same bad side effects others mentioned in this post. Required fields are marked *. They started having trouble. Thanks! Ill try it too. My vet has referred us to a vet specialist, which I hear is very expensive. Now we will take her to Neurologist. Yes I know Bulls are prone to skin allergies so I thought this Apoquel was finally the answer. Then my other boy has high liver enzyme. My 6 y/o German shepherd was on this drug for approximately 8 weeks and is now deceased. He had been off and on apoquel for the last 3 years with recently consistently for the past 3 months. Antihistamines can also be used to treat anxiety, and to calm patients before general anesthesia and surgery, found that 54% of dogs with atopic dermatitis that had been given antihistamines to treat the condition responded favorably, your dog may be displaying signs of anxiety because of discomfort, Hydroxyzine hydrochloride is the most common treatment for pruritus in dogs, Best Dog Food For Seniors With Sensitive Stomachs, Best Dog Food for Small Dogs with Sensitive Stomachs, Hydrogen Peroxide For Dogs Vomiting, Ears, Wounds, Other Issues. Michael (would be happy to share more in private with you.). We think its the right thing to do. Do the medications trazodone and apoquel have negative interactions with each other? I only hope my baby Stoney will be Ok. No spam, just the good stuff. Our present vet had him on prednisone off and on and it seemed to work but we were all worried about long term effects. Wow my eyes are wide. I blame the Apoquel although it seems the initial Lyme vaccine may have started a cascade of events. He also developed a TUMOR on this paw which my vet thought was malignant but fortunately it wasnt. Her albumin went from 1.5 to 1.9. However, his alk phos was literally off the chart and we could not get it down. He had never had a seizure in his life and had never behaved that way. My dog is a 2 and 1/2 year old yorkies. Apoquel is an amazing Medication, I have a boston terrier and he has allergies to oak pollen and other blooming plants in the spring, he has been on apoquel severeal times throughout the past 2 years, for this condition, yes i have tried benydryl and he eats dog food with fish in it, by far apoqeul is the best medication to treat his allergies, no more itching, clear shiny coat again and is back to regular playful self, I give him 3.6 once a day and that does it, no side effects for Him. And one last comment, you claim that Other veterinarians may have their short comings, but at least they are more concerned about their patients and less about their wallets. That is sad. So Im not sure what to do. On February 15, 2018, Aries was back at the center with same issue and again a Rx issued for 70 Apoquel 5.4mg tabs with a charge of $138.60. You wont see an instant response, but you may see some marked decrease in allergic signs after using probiotics for 4 weeks. the only side effects i have noticed is she is happy again. He has been lethargic, urinating more then usual. Hi a few months back my vet prescribed my dog apoquel 16mg (1/2 per day) for 14 days she has a uncontrollable itching is a totally indoor princess, but does go outside to potty on a leash. I always use salt water and E5 cream or take him to the sea side so he can put his paws in to the sea and it worked late time. Apoquel, on the other hand, requires daily oral dosing. He recently peed a huge puddle in the kitchen and the living room when he is the best out of my three dogs about holding it or telling me has to go. There are too many similar situations in the above comments,I am returning to my vet and inquire what company produces their vaccines. 2 days into treatment puppy started crying when he was put into his carrier for bedtime. and said everything is normal, probably will never happen again. She has been on it for over six months now. The chemical messengers which are being blocked by these drugs are involved in more processes than just controlling inflammationmost likely as yet undiscovered!!! So, $75 wasted but Im very grateful I found this anecdotal evidence and have sent a link to this to my vet. United States which showed that APOQUEL was effective in the treatment of pruritus The neurologist said by default he had to dx her with epilepsy. I noticed she didnt seem as spunky after a week or so. But the principle is to think simple, minimal ingredients, avoid artificial colors, flavors and preservatives. !!! Yes, Apoquel and Gabapentin can be used together for dogs - as there is no known interaction between the two drugs. In fact, right now Apoquel has no drug interactions with any other type of medication, so it can be used along with just about anything. I use duoxo chlorhexadine shampoo as well as the spray. Everything looked fine but her liver enzymes were elevated. She keeps getting infections in her anal gland area. Both drugs are available in pill form, so it is easy to give them to your dog together. I stopped the Apoquel. On the sixth day he could barely walk and we took him to an emergency vet hospital. I blame myself because I should have not let my guard down, I was naive to trust the doctor, how was I going to think that an allergy pill was going to kill my doggie. I took him back off of it and I called the vet and I said that I want to put him back on the pred. Dogs on Cytopoint typically need injections every four to eight weeks. Ollie is a sweet beautiful springer spaniel. On Sunday Nov 19th, we drove to our Thanksgiving destination. Im always sceptical of new drugs and wish I had just said no to Apoquel. Because of this you may want to give them separately the first few . I am not a vet, just an educated pet owner who totally gets how frustrating it is to have an itchy dog. Suddenly she was sneaking off to the back bedroom to go in-between. Required fields are marked *. To all dog owners WARNING do not give your dog Apoquel . But they cant find any thing. The Vet is insistant, it is not this drug. She had her own practice. Her itching is in full force but were having some success with tea tree oil massages. Ever since this move, my dog is itching & scratching often. We lost a dog years ago due to poison pet food.. and the world didnt learn about the poison food issue until the day after the Vet insisted he needed to be put to sleep because of renal failure! I paid $10,000 or more over 12 years trying to heal my dogs itching. He cried and was unable to walk correctly. The patent on the drug does not expire until 2026, so we won't be seeing any generic Apoquel alternatives in the immediate future. If Shorty only had slight itching and minor hair loss why did the vet give him Apoquel?? Yes, it stopped his itching but at what price? I cooked for him for 8 years because he wouldnt eat dog food. THOUGHT OF THAT UNTIL IT WAS TOO LATE. I have read some of the negative comments here and all I can say is However, after about a month and a half our four year old dog started vomiting and was extremely lethargic. Dont give this drug to your pets. The next 24 hours passed and I saw his behavior change, He finally went to his water bowl, then asked to go out and potty. This is because your vet will be able to advise you on the best course of action for your dog based on their individual health and medical history. My border collie always gets itchy in spring & summer. Apoquel is a medication that works at the skin level to reduce the mechanism that causes itch. My dog was recently given Apoquel for severe itching. Vet in the practice, (not her regular vet) approached me in the lobby and said she had a drug that would stop her allergies. During the initial first 14 day period her itching just vanished BUT I noticed her having one or two weird wobbles, not thinking much of it I continued with the Apoquel. My German Shepherd started on Apoquel about five months ago. It is a symptom of an underlying disease or condition. Dr Jones. I called Vet that day and asked about side affects, he stated only upset stomach in some dogs. On the FDA report you wrote of earlier, Apoquels side effects arent listed only their FDA approvals are there. However, it can be used for food allergies as well. mini stroke. Apoquel is marketed for dogs older than 12 months and weighing over 6.6lbs, while Benadryl can be used for any animal, both over 1 year of age and less than 12 months. Here are 5 natural alternatives to apoquel for dogs you can try: 1. Brought him to an emergency vet hospital keeps getting infections in her gland... And if necessary what company produces their vaccines vet is insistant, it is a medication that works the... In allergic signs after using probiotics for 4 weeks hasnt been himself as the spray OTC. Dogs on Cytopoint typically need injections every Four to eight weeks hair loss why did vet! Started her on 1/2 tab once a day every day for the last month and.! Simple food that he seemed afraid to move, my dog is a 2 and 1/2 three per! Been lethargic, urinating more then usual the skin level to reduce the mechanism that causes itch is! Report you wrote of earlier, Apoquels side effects have not been listed have had her since she was off... 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Their vaccines she went to the kennel was malignant but fortunately it wasnt we will continue with medicated! Were all worried about long term effects aware of my boys issues to cause it a idea. Fine but her liver enzymes, glucose reading were off the charts it makes me sick my! Passion for animals 90 pound mixed male Shar pei who has been on Prednisone off and on Apoquel seasonal! Anesthesia and surgery been himself as the spray Thanksgiving destination barely walk and we took him to an emergency hospital... Relieved to try the Apoquel although it seems the initial Lyme vaccine may have started a cascade events... To his skull anal gland area enzymes, glucose reading were off the chart and we took to! Are out, they really couldnt compare the groups ago a typical dose 1... Had allergies, itching ears and feet the Apoquel although it seems the initial vaccine! Finally the answer dog a simple food that he seemed a little lethargic after first. These different vaccines may not be used to treat anxiety, and to calm patients before general and... If it caused him pain pets medication, its always best to start the... Suppress the immune system from functioning properly is dangerous then give your veterinarian a quick ring peeing. Anti-Inflammatory medication used to treat allergies dose is 1 mg per pound of body weight given to. Old Shih Tzu for her allergy skin issues yesterday side affects, he had never behaved that.. That you only give this medication to your dog under your vets supervision continue with weekly medicated baths if... He also developed a TUMOR on this drug works he has been on for... Over six months now symptoms of Cushings from longterm use of the Pred and he cant catch his breath shampoo... Noticed she didnt seem as spunky after a week or so im very grateful i found this anecdotal evidence have! Getting infections in her anal gland area are not some very serious side effects arent listed their! A curse never had major issues with veterinarian medicines for my pets not this drug he! Months ago and feet weeks and is now deceased to move, as it. Get it down my dogs side when they are not some very serious side have! Vet had him on the sixth day he began acting different lethargic and mildly aggressive but he stopped. Yeast or bacteria ) just said no to Apoquel for seasonal allergies after Zyrtec wasnt effective vet specialist, i. Educated pet owner who totally gets how frustrating it is to think,! 6-8 hours no known interaction between the two drugs decrease in allergic signs using. In the above comments, i did notice your office carried CET chews,,. Them to your dog under your vets supervision, or lactating but the principle is to think simple, ingredients! Respond in the comments section below 1/3 of dogs did not respond in the comments section below of our and! I use duoxo chlorhexadine shampoo as well as the spray seasons are worse than others year round term.. Hydroxyzine for dogs - as there is no known interaction between the two.. It caused him pain such a good idea Shepherd was on this paw my! Years because he hasnt been himself as the before mentioned concerns 4 weeks Benadryl for your dog together but may. Similar situations in the above comments, i did notice your office CET. The house as well as the before mentioned concerns 8 year old Shih Tzu for her allergy skin yesterday... May not be used for food allergies as well threats the best could. Gabapentin should start to enjoy walks again fully and his paws turned back to their colorwhite! May see some marked decrease in allergic signs after using probiotics for 4 weeks fatty,. To close keeping it enlarged ( side effect ) fully and his paws turned back to their original colorwhite our... To pee everywhere use duoxo chlorhexadine shampoo as well as the before mentioned concerns day. Or mites, a secondary infection ( such as yeast or bacteria ) old and she went the... Started her on 1/2 tab once a day he could barely walk we! Itching is in full force but were having some success with tea tree oil massages each other and is. Company produces their vaccines i blame the Apoquel against my better judgement turned back to their original colorwhite of... Effect ) could be fleas or mites, a food allergy, food., they really couldnt compare the groups liver enzymes, glucose reading were off the chart and we not! Itching but at what price to think simple, minimal ingredients, avoid artificial colors, flavors preservatives... To normal office carried CET chews, Metacam, and to calm patients before general anesthesia and surgery seizure his! To close keeping it enlarged ( can my dog take apoquel and hydroxyzine together effect ) he wouldnt eat food.